Genetic Kinship Investigation from Blood Groups to DNA Markers

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Genetic Kinship Investigation from Blood Groups to DNA Markers.

The forensic application of hereditary characteristics became possible after the discovery of human blood groups by Karl Landsteiner in 1901. The foundation for their use in kinship investigation was laid by Emil von Dungern and Ludwig Hirschfeld in 1910 by clarification of the inheritance of the ABO groups. Up to the middle of the 20th century further red cell membrane systems were discovered....

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Selection of appropriate genetic markers to investigate kinship using DNA typing: A case report

  Introduction: Genetic identification is now a standard and efficient method for identifying individuals and investigating claimed kinship cases. Commercial kits based on autosomal STR and YSTR genetic markers are widely used for these investigations. Case Report: Two men were introduced by a judicial authority for genetic testing to identify and issue birth certificates for these individual...

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[Kinship determination using DNA markers].

BACKGROUND Autosomal and Y chromosome short tandem repeats (STRs) and mitochondrial DNA polymorphisms are the most commonly used molecular tools for determination of kinship. AIM To report a revision of 1,120 kinship cases (paternity and others) analyzed in our laboratory. MATERIAL AND METHODS Revision of all kinship cases analyzed between years 2001-2006. Autosomal and Y chromosome STRs an...

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Blood groups as genetic markers in glaucoma.

A series of 474 mixed cases of glaucoma was assessed to determine whether there were any genetic differences between different types of glaucoma. A careful distinction was made between chronic open angle glaucoma (COAG), acute and chronic angle closure glaucoma, ocular hypertension, low tension glaucoma, patients with large cup disc ratios, and various types of secondary glaucoma including pseu...

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Genetic Markers in Human Blood

The human population genetics incorporates study of biology and environmental factors, as well as the forces of micro-evolution leading to macro-evolution, which ultimately influences the structure of humanpopulations. In the present paper and attempt has been made to a give a brief review of the genetics and distribution of some of the polymorphic traits blood groups, human leucocyte antig...

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ژورنال

عنوان ژورنال: Transfusion Medicine and Hemotherapy

سال: 2012

ISSN: 1660-3818,1660-3796

DOI: 10.1159/000338850